Fine-tuning Nanotech to Target Cancer - Technology Review

Fine-tuning Nanotech to Target Cancer

Programmable nanoparticles have shown promise in early cancer trials, and may finally fulfill the promise of nanomedicine.

  • THURSDAY, MAY 3, 2012
  • BY SUSAN YOUNG

Programmable particle: Bind's drug-delivery nanoparticle (artist's rendering). 
Model & image by Digizyme, Inc.

The results of the human trials are startling. Even at a lower-than-usual dose, multiple lung metastases shrank or even disappeared after one patient received only two-hour-long intravenous infusions of an experimental cancer drug. Another patient saw her cervical tumor reduce by nearly 60 percent after six months of treatment. Though the drug trial—by Bind Biosciences in Cambridge, Massachusetts—of an experimental nanotechnology-based technique was designed simply to show whether the technology is safe, the encouraging results revive hopes that nanomedicine could realize its elusive promise.

- dave

David Warlick

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Fine-tuning Nanotech to Target Cancer - Technology Review

Fine-tuning Nanotech to Target Cancer

Programmable nanoparticles have shown promise in early cancer trials, and may finally fulfill the promise of nanomedicine.

  • THURSDAY, MAY 3, 2012
  • BY SUSAN YOUNG

Programmable particle: Bind's drug-delivery nanoparticle (artist's rendering). 
Model & image by Digizyme, Inc.

The results of the human trials are startling. Even at a lower-than-usual dose, multiple lung metastases shrank or even disappeared after one patient received only two-hour-long intravenous infusions of an experimental cancer drug. Another patient saw her cervical tumor reduce by nearly 60 percent after six months of treatment. Though the drug trial—by Bind Biosciences in Cambridge, Massachusetts—of an experimental nanotechnology-based technique was designed simply to show whether the technology is safe, the encouraging results revive hopes that nanomedicine could realize its elusive promise.

- dave

David Warlick

... Sent from my iPad ...

Salford scientists reveal the 'sound of Stonehenge' | UK news | guardian.co.uk

Salford scientists reveal the 'sound of Stonehenge' 
Stonehenge
Bits missing. But when it was all in place, there'd have been booms, rumbles, echoes and reverberations. Photograph: Jason Hawkes/Getty

Salford's clever academics, who once took me shopping in a virtual supermarket – you sat in an armchair wearing a helmet and a glove – have now recreated the sound of Stonehenge.

We are nowhere nearer cracking the mystery of the monument as a result; but who would want to be? Apart from all the mountains of remaindered books of theories, a puzzle solved is never as gripping as a conundrum still under way.

But the four-year project by Dr Bruno Fazenda and colleagues atHuddersfield and Bristol universities, has established how the shouts, speeches, songs or sacrificial screams would have sounded, whatever material they may have contained. The method has been a painstaking piece of 'archaeoacoustics', a relatively new discipline which reveals the sound quality of buildings from the past.

- dave

David Warlick

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Article: Hong Kong student behind Steve Jobs-Apple logo tribute lands Coca Cola ad project

Jon Russell
cocacola2 520x245 Hong Kong student behind Steve Jobs Apple logo tribute lands Coca Cola ad projectCOCACOLA2 520X245 PHOTO

Hong Kong design stu­dent Jonathan Mak Long, who gained glob­al recog­ni­tion last year for a unique logo trib­ute to Steve Jobs, has seen his career begin to take off after the young design­er land­ed an advert for Coca Cola fol­low­ing his Apple suc­cess.

Hong Kong student behind Steve Jobs-Apple logo tribute lands Coca Cola ad project
http://thenextweb.com/dd/2012/04/19/hong-kong-student-behind-steve-jobs-apple-logo-tribute-lands-coca-cola-ad-project/

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David Warlick

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Article: GM Tests a Self-Driving Cadillac

GM Tests a Self-Driving Cadillac

KEVIN BULLIS 04/20/2012

Google isn’t the only company with a self-driving car. BMW, Volvo, and Volkswagen have test versions that can drive themselves in some situations.  Many automakers offer features that aretaking over more and more aspects of driving. And today GM announced it is road testing a Cadillac that can steer itself on the highway using sensors and GPS data. Many of the technologies required, such as lane departure warning systems and adaptive cruise control, are available on two of its 2013 luxury cars.

The new technology is called “super cruise,” no doubt to make it sound like merely an extension of cruise control, a automatic system drivers are already comfortable with.

Here’s a video of the system in action


GM Tests a Self-Driving Cadillac
http://www.technologyreview.com/blog/energy/27786/

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David Warlick

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A Startup Puts the Internet in Your Couch Cushions

COMPUTING

A Startup Puts the Internet in Your Couch Cushions

Sensor-filled Ninja Blocks connect the Web with whatever's nearby.

  • MONDAY, APRIL 16, 2012
  • BY RACHEL METZ
  • Whoever has been stealing Mark Wotton's newspaper should look out: He's formulating a revenge plan, and it involves ninjas.

Net ninja: Sensor-laden, Web-connected Ninja Blocks can carry out preset actions in response to stimuli. For example, you might tell the block to sound an alarm when your cat jumps on your sofa. 

A Startup Puts the Internet in Your Couch Cushions
http://www.technologyreview.com/computing/40193/

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David Warlick

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Article: The Computing Trend that Will Change Everything

The Computing Trend that Will Change Everything

Computing isn't just getting cheaper. It's becoming more energy efficient. That means a world populated by ubiquitous sensors and streams of nanodata.

  • MONDAY, APRIL 9, 2012
  • BY JONATHAN KOOMEY

Less energy: The number of computations carried out by computers for the same energy has been increasing by a factor of two every 1.5 years. 
Jonathan Koomey

The performance of computers has shown remarkable and steady growth, doubling every year and a half since the 1970s. What most folks don't know, however, is that the electrical efficiency of computing (the number of computations that can be completed per kilowatt-hour of electricity used) has also doubled every year and a half since the dawn of the computer age.

The Computing Trend that Will Change Everything
http://www.technologyreview.com/business/40016/

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David Warlick

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Why It Took So Long to Invent the Wheel


Why It Took So Long to Invent the Wheel

Scientific American

The tricky thing about the wheel is not conceiving of a cylinder rolling on its edge. It's figuring out how to connect a stable, stationary platform to that cylinder

WHEELS OF WONDER: A wheeled figurine from the New World, probably made in Veracruz between 100 B.C. and 800 A.D.

Wheels are the archetype of a primitive, caveman-level technology. But in fact, they're so ingenious that it took until 3500 B.C. for someone to invent them. By that time - it was the Bronze Age - humans were already casting metal alloys, constructing canals and sailboats, and even designing complex musical instruments such as harps.

The tricky thing about the wheel is not conceiving of a cylinder rolling on its edge. It's figuring out how to connect a stable, stationary platform to that cylinder.

- dave

David Warlick

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Article: 10 Futuristic Products in Development Now


10 Futuristic Products in Development Now
http://mashable.com/2012/03/15/sci-fi-visions-future/

1. INVISIBLE CAR

To pro­mote its new fuel cell vehi­cle, which has zero exhaust emis­sions, Mer­cedes pulled a stunt that showed off an "invis­i­ble" car with incred­i­bly low envi­ron­men­tal impact.

Although Mer­cedes says the hydrogen-powered drive sys­tem is "ready for series production," it's spec­u­lat­ed to not be in com­er­cial­iza­tion until 2014.

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David Warlick

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Article: Your Reputation Is Your Résumé

Your Reputation Is Your Résumé

Employers are screening for job candidates who have created a presence online. For many young people, that's a chance to shine.

  • FRIDAY, FEBRUARY 24, 2012
  • BY TED GREENWALD

Technology Review

Your Reputation Is Your Résumé
http://www.technologyreview.com/business/39785/

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David Warlick

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